Do you people even have a clue?
The "heavy" designation refers to an aircraft that is certificated to operate at a maximum gross takeoff weight greater than 255,000 pounds. It doesn't matter what it actually does weigh on takeoff, but whether or not it it is certificated to operate above 255,000 pounds.
From http://www.faa.gov/regulations_policies/orders_notices/air_traffic_orders/media/7110.65R.pdf
"a. Heavy. Aircraft capable of takeoff weights of
more than 255,000 pounds whether or not they are
operating at this weight during a particular phase of
flight.
b. Large. Aircraft of more than 41,000 pounds,
maximum certificated takeoff weight, up to
255,000 pounds.
c. Small. Aircraft of 41,000 pounds or less
maximum certificated takeoff weight."
Kevin is also correct, except I have been a 757 pilot since 1999 and the -200 are not "heavy" as max weight is only 228,000. But the -300 is considered heavy because it is over 255,000. One interesting note, some -200's used as ETOPS are exactly 255,000, but the book says "more than" 255,000 so the ETOPS 757's, unless more than 255,000 do not use the "heavy" designator.
Those interested further should check the link I posted as it will say "757 and heavy jets" when referring to wake turbulence and separation.
But the guy asking the question only asked what heavy meant, not about wake turbulence or aircraft separation.