It is kind of funny to see how experience changes peoples oppinions.
Personally, I don't fly much single engine IFR because of where I live and what I fly. It is usually either ice or thunderstorms around here, maybe 10 good IFR flying days a year, but that is not the case in a most places.
It is an issue of comfort, I have never had any kind of serious issue that has put me in a position to make a forced landing, because of that I am not too opposed to flying in the soup. I just don't enjoy it.
You're asking "is it safe?" The answer is no. Flying isn't safe. Driving isn't safe, Living isn't safe. We do all those things anyways because the risks are acceptable, and we usually do things to minimize the risks. If I'm in a position where I need to fly in some bad weather, a few things have to happen or I just won't do it. I want some recent experience, a few landings, approaches, some navigation work, how much in what amount of time is dependant on the situation, ovbiously never less than what the FAA requires, but it does depend on a lot of things. There are some aiplanes that I would refuse to fly. Maybe not a particular type, but there could just be 5 182's around I could take but there are 2 of them I would just refuse to fly in bad weather for whatever reasons. And the weather can't be too bad, I still want to be able to get down and not have to fly an approach to minimums. If that is the case there better be a close alternate with better weather.
As long as I'm not going out of my comfort zone I'll do it (that goes for anything), everyone has a different level of comfort. Some peoples level of comfort can put them into a dangerous situation, my level of comfort has done it to me before, and then my level of comfort changed.